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Director/Sr. Director, Therapeutic Antibody Discovery

Full-time at Mab-Venture Biopharma in Shanghai


1) Select tractable molecular targets with excellent biological rationale for the therapeutic antibody discovery project teams across multiple disease areas;
2) Lead the project teams to establish high-throughput and robust functional assays for lead antibody screening;
3) Drive department-wide efforts to isolate, clone, engineer, and optimize new biologic entities with excellent in vitro and in vivo biological functions and developability using a variety of technologies;
4) Support CMC development and IND-enabling studies for lead candidates.

1) Ph.D. with at least 10 years of working experience in Oncology, Immunology, Biochemistry, Molecular and Structural Biology or related discipline;
2) Prior experience leading therapeutic antibody discovery projects and managing project team(s), industry experience from overseas strongly preferred;
3) Familiarity with antibody structure, properties and sequences;
3) Prior experience in the design, execution, and analysis of immunological, biochemical, and/or cellular assays (e.g., ELISA, ELISPOT, FCM, Western blot, immunoprecipitation, MLR, etc.) and assay results;
4) Expertise utilizing techniques for antibody structure modeling, engineering, humanization, affinity measurement and affinity maturation;
5) Ability to demonstrate autonomy, good judgement and inspiration of others;
6) Ability to set aggressive goals and clear direction and to measure performance for the project team(s);
7) Excellent written and verbal communication skills in both English and Mandarin.

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Published at 20-Sep-2017
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